Entry Detail



General Information

Database ID:SKCM03196
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FUCA2
Full Name:alpha-L-fucosidase 2
Category:mRNA
Synonyms:dJ20N2.5
Chromosome:chr6
Strand:-
Coordinate:
Start Site(bp):143494811End Site(bp):143511690
Gene Summary:This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. [provided by RefSeq, Aug 2010]
External Links:
Ensembl ID:ENSG00000001036
HGNC ID:HGNC:4008
Entrez Gene:2519



Expression Profile of FUCA2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
YES
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-107
YES
YES
YES
hsa-miR-145-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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