ctcRbase

Entry Detail

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General Information

Database ID: SKCM03203 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: HMGA1 Full Name: high mobility group AT-hook 1 Category: mRNA Synonyms: HMG-R|HMGA1A|HMGIY Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 34236873 End Site(bp): 34246231 Gene Summary: This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000137309 HGNC ID: HGNC:5010 Entrez Gene: 3159

Expression Profile of HMGA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1297 YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-138-5p YES NO YES hsa-miR-142-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-296-5p YES NO YES hsa-miR-424-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-625-5p YES NO NO hsa-miR-665 YES NO YES hsa-miR-758-3p YES NO YES hsa-miR-98-5p YES YES YES Display: