ctcRbase

Entry Detail

---



General Information

Database ID: SKCM03229 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PEX19 Full Name: peroxisomal biogenesis factor 19 Category: mRNA Synonyms: D1S2223E|HK33|PBD12A|PMP1|PMPI|PXF|PXMP1 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 160276812 End Site(bp): 160286348 Gene Summary: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010] External Links: Ensembl ID: ENSG00000162735 HGNC ID: HGNC:9713 Entrez Gene: 5824

Expression Profile of PEX19 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-183-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-24-3p YES NO YES hsa-miR-28-3p YES NO YES hsa-miR-31-5p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-346 YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-493-3p YES NO YES hsa-miR-497-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-875-5p YES YES NO Display: