ctcRbase

Entry Detail

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General Information

Database ID: SKCM03236 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MGME1 Full Name: mitochondrial genome maintenance exonuclease 1 Category: mRNA Synonyms: C20orf72|DDK1|MTDPS11|bA504H3.4 Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 17968913 End Site(bp): 17991122 Gene Summary: The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015] External Links: Ensembl ID: ENSG00000125871 HGNC ID: HGNC:16205 Entrez Gene: 92667

Expression Profile of MGME1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-98-5p YES YES NO Display: