ctcRbase

Entry Detail

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General Information

Database ID: SKCM03242 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: POLR2B Full Name: RNA polymerase II subunit B Category: mRNA Synonyms: POL2RB|RPB2|hRPB140 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 56977722 End Site(bp): 57031168 Gene Summary: This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] External Links: Ensembl ID: ENSG00000047315 HGNC ID: HGNC:9188 Entrez Gene: 5431

Expression Profile of POLR2B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-495-3p YES YES NO Display: