ctcRbase

Entry Detail

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General Information

Database ID: SKCM03265 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MYD88 Full Name: MYD88, innate immune signal transduction adaptor Category: mRNA Synonyms: MYD88D Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 38138478 End Site(bp): 38143022 Gene Summary: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] External Links: Ensembl ID: ENSG00000172936 HGNC ID: HGNC:7562 Entrez Gene: 4615

Expression Profile of MYD88 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-147a YES NO NO hsa-miR-185-5p YES YES NO hsa-miR-187-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-326 YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-330-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-365a-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-455-5p YES YES NO Display: