ctcRbase

Entry Detail

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General Information

Database ID: SKCM03266 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NDUFS1 Full Name: NADH:ubiquinone oxidoreductase core subunit S1 Category: mRNA Synonyms: CI-75Kd|CI-75k|PRO1304 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 206114817 End Site(bp): 206159603 Gene Summary: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] External Links: Ensembl ID: ENSG00000023228 HGNC ID: HGNC:7707 Entrez Gene: 4719

Expression Profile of NDUFS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-429 YES YES NO Display: