ctcRbase

Entry Detail

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General Information

Database ID: SKCM03268 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: COIL Full Name: coilin Category: mRNA Synonyms: CLN80|p80-coilin Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 56938187 End Site(bp): 56961054 Gene Summary: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000121058 HGNC ID: HGNC:2184 Entrez Gene: 8161

Expression Profile of COIL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-142-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-206 YES YES YES hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-488-3p YES YES YES hsa-miR-490-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-613 YES YES YES hsa-miR-98-5p YES YES YES Display: