| ncRNA Symbol: | PRPF8 |
| Full Name: | pre-mRNA processing factor 8 |
| Category: | mRNA |
| Synonyms: | HPRP8|PRP8|PRPC8|RP13|SNRNP220 |
| Chromosome: | chr17 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 1650629 | End Site(bp): | 1684882 |
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| Gene Summary: | Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008] |
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