ctcRbase

Entry Detail

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General Information

Database ID: SKCM03376 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MMS22L Full Name: MMS22 like, DNA repair protein Category: mRNA Synonyms: C6orf167|dJ39B17.2 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 97142161 End Site(bp): 97283217 Gene Summary: The protein encoded by this gene forms a complex with tonsoku-like, DNA repair protein (TONSL), and this complex recognizes and repairs DNA double-strand breaks at sites of stalled or collapsed replication forks. The encoded protein also can bind with the histone-associated protein NFKBIL2 to help regulate the chromatin state at stalled replication forks. Finally, this gene appears to be overexpressed in most lung and esophageal cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017] External Links: Ensembl ID: ENSG00000146263 HGNC ID: HGNC:21475 Entrez Gene: 253714

Expression Profile of MMS22L Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-15a-5p YES NO NO hsa-miR-15b-5p YES NO NO hsa-miR-16-5p YES NO NO hsa-miR-186-5p YES YES NO hsa-miR-187-3p YES YES NO hsa-miR-195-5p YES NO NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-342-3p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-381-3p YES YES NO hsa-miR-424-5p YES NO NO hsa-miR-429 YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-503-5p YES NO NO hsa-miR-876-5p YES YES NO hsa-miR-96-5p YES YES NO hsa-miR-98-5p YES YES NO Display: