Entry Detail



General Information

Database ID:SKCM03382
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ALDH1A1
Full Name:aldehyde dehydrogenase 1 family member A1
Category:mRNA
Synonyms:ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1
Chromosome:chr9
Strand:-
Coordinate:
Start Site(bp):72900662End Site(bp):73080442
Gene Summary:The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
External Links:
Ensembl ID:ENSG00000165092
HGNC ID:HGNC:402
Entrez Gene:216



Expression Profile of ALDH1A1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1297
YES
YES
NO
hsa-miR-132-3p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-212-3p
YES
YES
NO
hsa-miR-21-5p
YES
YES
NO
hsa-miR-221-3p
YES
YES
NO
hsa-miR-222-3p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-590-5p
YES
YES
NO
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