ctcRbase

Entry Detail

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General Information

Database ID: SKCM03401 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MED14 Full Name: mediator complex subunit 14 Category: mRNA Synonyms: CRSP150|CRSP2|CSRP|CXorf4|DRIP150|EXLM1|RGR1|TRAP170 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 40648306 End Site(bp): 40735858 Gene Summary: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000180182 HGNC ID: HGNC:2370 Entrez Gene: 9282

Expression Profile of MED14 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-129-5p YES NO YES hsa-miR-137 YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-215-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-340-5p YES YES YES hsa-miR-362-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES NO NO hsa-miR-582-5p YES NO YES hsa-miR-96-5p YES YES YES Display: