Entry Detail



General Information

Database ID:SKCM03429
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SH3PXD2B
Full Name:SH3 and PX domains 2B
Category:mRNA
Synonyms:FAD49|FTHS|HOFI|KIAA1295|TKS4|TSK4
Chromosome:chr5
Strand:-
Coordinate:
Start Site(bp):172325000End Site(bp):172454523
Gene Summary:This gene encodes an adapter protein that is characterized by a PX domain and four Src homology 3 domains. The encoded protein is required for podosome formation and is involved in cell adhesion and migration of numerous cell types. Mutations in this gene are the cause of Frank-ter Haar syndrome (FTHS), and also Borrone Dermato-Cardio-Skeletal (BDCS) syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
External Links:
Ensembl ID:ENSG00000174705
HGNC ID:HGNC:29242
Entrez Gene:285590



Expression Profile of SH3PXD2B Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1271-5p
YES
YES
YES
hsa-miR-133a-3p
YES
NO
YES
hsa-miR-133b
YES
NO
YES
hsa-miR-137
YES
NO
YES
hsa-miR-1-3p
YES
YES
YES
hsa-miR-182-5p
YES
NO
YES
hsa-miR-206
YES
YES
YES
hsa-miR-299-3p
YES
YES
NO
hsa-miR-29a-3p
YES
NO
YES
hsa-miR-29b-3p
YES
NO
YES
hsa-miR-29c-3p
YES
NO
YES
hsa-miR-382-5p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-613
YES
YES
YES
hsa-miR-9-5p
YES
NO
YES
hsa-miR-96-5p
YES
YES
YES
Display: