Entry Detail



General Information

Database ID:SKCM03439
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:LETM1
Full Name:leucine zipper and EF-hand containing transmembrane protein 1
Category:mRNA
Synonyms:SLC55A1
Chromosome:chr4
Strand:-
Coordinate:
Start Site(bp):1811479End Site(bp):1856247
Gene Summary:This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009]
External Links:
Ensembl ID:ENSG00000168924
HGNC ID:HGNC:6556
Entrez Gene:3954



Expression Profile of LETM1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1297
YES
YES
YES
hsa-miR-1-3p
YES
NO
YES
hsa-miR-197-3p
YES
YES
NO
hsa-miR-206
YES
NO
YES
hsa-miR-26a-5p
YES
YES
YES
hsa-miR-26b-5p
YES
YES
YES
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-330-3p
YES
NO
YES
hsa-miR-495-3p
YES
YES
NO
hsa-miR-613
YES
NO
YES
hsa-miR-7-5p
YES
YES
NO
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