ctcRbase

Entry Detail

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General Information

Database ID: SKCM03469 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PSMC3IP Full Name: PSMC3 interacting protein Category: mRNA Synonyms: GT198|HOP2|HUMGT198A|ODG3|TBPIP Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 42572315 End Site(bp): 42577831 Gene Summary: This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011] External Links: Ensembl ID: ENSG00000131470 HGNC ID: HGNC:17928 Entrez Gene: 29893

Expression Profile of PSMC3IP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-873-5p YES YES NO Display: