ctcRbase

Entry Detail

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General Information

Database ID: SKCM03475 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CHD4 Full Name: chromodomain helicase DNA binding protein 4 Category: mRNA Synonyms: CHD-4|Mi-2b|Mi2-BETA|SIHIWES Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 6570083 End Site(bp): 6607476 Gene Summary: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000111642 HGNC ID: HGNC:1919 Entrez Gene: 1108

Expression Profile of CHD4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-98-5p YES YES YES Display: