ctcRbase

Entry Detail

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General Information

Database ID: SKCM03514 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EIF2B5 Full Name: eukaryotic translation initiation factor 2B subunit epsilon Category: mRNA Synonyms: CACH|CLE|EIF-2B|EIF2Bepsilon|LVWM Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 184135038 End Site(bp): 184145311 Gene Summary: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009] External Links: Ensembl ID: ENSG00000145191 HGNC ID: HGNC:3261 Entrez Gene: 8893

Expression Profile of EIF2B5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-497-5p YES YES YES Display: