Entry Detail



General Information

Database ID:SKCM03546
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GIGYF2
Full Name:GRB10 interacting GYF protein 2
Category:mRNA
Synonyms:GYF2|PARK11|PERQ2|PERQ3|TNRC15
Chromosome:chr2
Strand:+
Coordinate:
Start Site(bp):232697299End Site(bp):232860575
Gene Summary:This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
External Links:
Ensembl ID:ENSG00000204120
HGNC ID:HGNC:11960
Entrez Gene:26058



Expression Profile of GIGYF2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-122-5p
YES
YES
NO
hsa-miR-1321
YES
NO
NO
hsa-miR-143-3p
YES
YES
YES
hsa-miR-18a-5p
YES
YES
NO
hsa-miR-18b-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-217
NO
YES
YES
hsa-miR-22-3p
YES
YES
NO
hsa-miR-224-5p
YES
YES
NO
hsa-miR-25-3p
YES
NO
YES
hsa-miR-30a-5p
YES
YES
YES
hsa-miR-30b-5p
YES
YES
YES
hsa-miR-30c-5p
YES
YES
YES
hsa-miR-30d-5p
YES
YES
YES
hsa-miR-30e-5p
YES
YES
YES
hsa-miR-31-5p
YES
YES
NO
hsa-miR-32-5p
YES
NO
YES
hsa-miR-329-3p
YES
NO
NO
hsa-miR-330-3p
YES
NO
YES
hsa-miR-361-5p
YES
YES
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-363-3p
YES
NO
YES
hsa-miR-367-3p
YES
NO
YES
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-376a-3p
YES
YES
NO
hsa-miR-376b-3p
YES
YES
NO
hsa-miR-433-3p
YES
YES
NO
hsa-miR-874-3p
YES
YES
NO
hsa-miR-92a-3p
YES
NO
YES
hsa-miR-92b-3p
YES
NO
YES
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