ctcRbase

Entry Detail

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General Information

Database ID: SKCM03563 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ARNT Full Name: aryl hydrocarbon receptor nuclear translocator Category: mRNA Synonyms: HIF-1-beta|HIF-1beta|HIF1-beta|HIF1B|HIF1BETA|TANGO|bHLHe2 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 150809705 End Site(bp): 150876768 Gene Summary: This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] External Links: Ensembl ID: ENSG00000143437 HGNC ID: HGNC:700 Entrez Gene: 405

Expression Profile of ARNT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-153-3p YES NO YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-448 YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-9-5p YES YES NO Display: