ctcRbase

Entry Detail

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General Information

Database ID: SKCM03581 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FLNB Full Name: filamin B Category: mRNA Synonyms: ABP-278|ABP-280|AOI|FH1|FLN-B|FLN1L|LRS1|SCT|TABP|TAP Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 58008400 End Site(bp): 58172251 Gene Summary: This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009] External Links: Ensembl ID: ENSG00000136068 HGNC ID: HGNC:3755 Entrez Gene: 2317

Expression Profile of FLNB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES NO hsa-miR-138-5p NO YES YES hsa-miR-145-5p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-346 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-876-5p YES YES NO Display: