ctcRbase

Entry Detail

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General Information

Database ID: SKCM03604 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TOP1 Full Name: DNA topoisomerase I Category: mRNA Synonyms: TOPI Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 41028818 End Site(bp): 41124487 Gene Summary: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000198900 HGNC ID: HGNC:11986 Entrez Gene: 7150

Expression Profile of TOP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-137 YES YES YES hsa-miR-139-5p YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-149-5p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-24-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-299-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-365a-3p YES YES NO hsa-miR-367-3p YES YES YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES YES hsa-miR-433-3p YES YES YES hsa-miR-448 YES YES NO hsa-miR-487a-3p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: