ctcRbase

Entry Detail

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General Information

Database ID: SKCM03618 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NCOR1 Full Name: nuclear receptor corepressor 1 Category: mRNA Synonyms: N-CoR|N-CoR1|PPP1R109|TRAC1|hN-CoR Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 16029157 End Site(bp): 16218185 Gene Summary: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010] External Links: Ensembl ID: ENSG00000141027 HGNC ID: HGNC:7672 Entrez Gene: 9611

Expression Profile of NCOR1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-149-5p YES YES YES hsa-miR-217 YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-760 YES NO YES Display: