ctcRbase

Entry Detail

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General Information

Database ID: SKCM03633 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TIMELESS Full Name: timeless circadian regulator Category: mRNA Synonyms: TIM|TIM1|hTIM Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 56416373 End Site(bp): 56449403 Gene Summary: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. [provided by RefSeq, Feb 2014] External Links: Ensembl ID: ENSG00000111602 HGNC ID: HGNC:11813 Entrez Gene: 8914

Expression Profile of TIMELESS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-187-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-429 YES YES NO hsa-miR-483-3p YES NO YES hsa-miR-551a YES YES NO hsa-miR-551b-3p YES YES NO hsa-miR-708-5p YES YES NO Display: