ctcRbase

Entry Detail

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General Information

Database ID: SKCM03642 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NPL Full Name: N-acetylneuraminate pyruvate lyase Category: mRNA Synonyms: C112|C1orf13|NAL|NPL1 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 182789293 End Site(bp): 182830384 Gene Summary: This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] External Links: Ensembl ID: ENSG00000135838 HGNC ID: HGNC:16781 Entrez Gene: 80896

Expression Profile of NPL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-140-5p YES YES YES hsa-miR-151a-3p YES NO YES hsa-miR-15b-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-93-5p YES YES NO Display: