Entry Detail



General Information

Database ID:SKCM03651
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:EIF4EBP2
Full Name:eukaryotic translation initiation factor 4E binding protein 2
Category:mRNA
Synonyms:4EBP2|PHASII
Chromosome:chr10
Strand:+
Coordinate:
Start Site(bp):70404379End Site(bp):70428618
Gene Summary:This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]
External Links:
Ensembl ID:ENSG00000148730
HGNC ID:HGNC:3289
Entrez Gene:1979



Expression Profile of EIF4EBP2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1252-5p
YES
NO
NO
hsa-miR-1271-5p
YES
NO
YES
hsa-miR-141-3p
YES
NO
YES
hsa-miR-145-5p
YES
NO
YES
hsa-miR-182-5p
YES
NO
YES
hsa-miR-193a-5p
YES
NO
YES
hsa-miR-200a-3p
YES
NO
YES
hsa-miR-21-5p
YES
NO
YES
hsa-miR-23a-3p
YES
YES
YES
hsa-miR-23b-3p
YES
YES
YES
hsa-miR-330-3p
YES
NO
YES
hsa-miR-495-3p
YES
YES
NO
hsa-miR-590-5p
YES
NO
YES
hsa-miR-7-5p
YES
NO
YES
hsa-miR-96-5p
YES
NO
YES
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