Entry Detail



General Information

Database ID:SKCM03680
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:TDP2
Full Name:tyrosyl-DNA phosphodiesterase 2
Category:mRNA
Synonyms:AD022|EAP2|EAPII|TTRAP|dJ30M3.3|hTDP2
Chromosome:chr6
Strand:-
Coordinate:
Start Site(bp):24649977End Site(bp):24667033
Gene Summary:This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000111802
HGNC ID:HGNC:17768
Entrez Gene:51567



Expression Profile of TDP2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1-3p
YES
YES
NO
hsa-miR-183-5p
YES
YES
NO
hsa-miR-206
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-486-5p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-613
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
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