ctcRbase

Entry Detail

---



General Information

Database ID: SKCM03701 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NUMB Full Name: NUMB, endocytic adaptor protein Category: mRNA Synonyms: C14orf41|S171|c14_5527 Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 73275107 End Site(bp): 73463642 Gene Summary: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] External Links: Ensembl ID: ENSG00000133961 HGNC ID: HGNC:8060 Entrez Gene: 8650

Expression Profile of NUMB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-146a-5p YES YES YES hsa-miR-146b-5p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-219a-5p YES NO YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES YES hsa-miR-448 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-9-5p YES YES NO hsa-miR-96-5p YES NO YES Display: