ctcRbase

Entry Detail

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General Information

Database ID: SKCM03726 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: P4HA1 Full Name: prolyl 4-hydroxylase subunit alpha 1 Category: mRNA Synonyms: P4HA Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 73007217 End Site(bp): 73096974 Gene Summary: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000122884 HGNC ID: HGNC:8546 Entrez Gene: 5033

Expression Profile of P4HA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-1297 YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-197-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-506-3p YES YES YES hsa-miR-708-5p YES YES NO Display: