ctcRbase

Entry Detail

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General Information

Database ID: SKCM03745 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TCF7L2 Full Name: transcription factor 7 like 2 Category: mRNA Synonyms: TCF-4|TCF4 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 112950250 End Site(bp): 113167678 Gene Summary: This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010] External Links: Ensembl ID: ENSG00000148737 HGNC ID: HGNC:11641 Entrez Gene: 6934

Expression Profile of TCF7L2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p NO YES YES hsa-miR-1297 NO YES YES hsa-miR-1323 YES NO NO hsa-miR-132-3p YES YES YES hsa-miR-135a-5p NO YES YES hsa-miR-135b-5p NO YES YES hsa-miR-1-3p NO YES YES hsa-miR-181a-5p NO YES YES hsa-miR-181b-5p NO YES YES hsa-miR-181c-5p NO YES YES hsa-miR-181d-5p NO YES YES hsa-miR-183-5p NO YES YES hsa-miR-191-5p NO YES YES hsa-miR-194-5p NO YES YES hsa-miR-206 NO YES YES hsa-miR-212-3p YES YES YES hsa-miR-216b-5p NO YES YES hsa-miR-217 NO YES YES hsa-miR-221-3p NO YES YES hsa-miR-222-3p NO YES YES hsa-miR-22-3p NO YES YES hsa-miR-26a-5p NO YES YES hsa-miR-26b-5p NO YES YES hsa-miR-328-3p NO YES YES hsa-miR-377-3p NO YES YES hsa-miR-379-5p YES YES NO hsa-miR-494-3p NO YES YES hsa-miR-503-5p YES YES NO hsa-miR-543 NO YES YES hsa-miR-548o-3p YES NO NO hsa-miR-613 NO YES YES hsa-miR-653-5p YES YES NO hsa-miR-875-5p NO YES YES hsa-miR-96-5p NO YES YES Display: