ctcRbase

Entry Detail

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General Information

Database ID: SKCM03768 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: VKORC1L1 Full Name: vitamin K epoxide reductase complex subunit 1 like 1 Category: mRNA Synonyms: - Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 65873267 End Site(bp): 65959563 Gene Summary: This gene encodes an enzyme important in the vitamin K cycle, which is involved in the carboxylation of glutamate residues present in vitamin K-dependent proteins. The encoded enzyme catalyzes the de-epoxidation of vitamin K 2,3-epoxide. Oxidative stress may upregulate expression of this gene and the encoded protein may protect cells and membrane proteins form oxidative damage. This gene and a related gene (Gene ID: 79001) may have arisen by gene duplication of an ancestral gene. [provided by RefSeq, Oct 2016] External Links: Ensembl ID: ENSG00000196715 HGNC ID: HGNC:21492 Entrez Gene: 154807

Expression Profile of VKORC1L1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-296-5p YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-369-3p YES NO NO hsa-miR-370-3p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-758-3p YES YES NO hsa-miR-875-5p YES YES YES hsa-miR-876-5p YES YES NO hsa-miR-93-5p YES YES NO Display: