ctcRbase

Entry Detail

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General Information

Database ID: SKCM03783 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ADAM19 Full Name: ADAM metallopeptidase domain 19 Category: mRNA Synonyms: FKSG34|MADDAM|MLTNB Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 157395534 End Site(bp): 157575775 Gene Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013] External Links: Ensembl ID: ENSG00000135074 HGNC ID: HGNC:197 Entrez Gene: 8728

Expression Profile of ADAM19 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-128-3p YES NO YES hsa-miR-1297 YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-150-5p YES YES YES hsa-miR-153-3p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-328-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-370-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-532-3p YES NO YES hsa-miR-874-3p YES YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: