Entry Detail



General Information

Database ID:SKCM03807
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SMPD1
Full Name:sphingomyelin phosphodiesterase 1
Category:mRNA
Synonyms:ASM|ASMASE|NPD
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):6390431End Site(bp):6394998
Gene Summary:The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
External Links:
Ensembl ID:ENSG00000166311
HGNC ID:HGNC:11120
Entrez Gene:6609



Expression Profile of SMPD1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-15a-5p
YES
YES
YES
hsa-miR-15b-5p
YES
YES
YES
hsa-miR-16-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
YES
hsa-miR-214-3p
YES
NO
NO
hsa-miR-346
YES
YES
NO
hsa-miR-34a-5p
YES
YES
NO
hsa-miR-34c-5p
YES
YES
NO
hsa-miR-424-5p
YES
YES
YES
hsa-miR-449a
YES
YES
NO
hsa-miR-449b-5p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-497-5p
YES
YES
YES
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