ctcRbase

Entry Detail

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General Information

Database ID: SKCM03852 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: HERC2 Full Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2 Category: mRNA Synonyms: D15F37S1|MRT38|SHEP1|jdf2|p528 Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 28111040 End Site(bp): 28322152 Gene Summary: This gene belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16. [provided by RefSeq, Mar 2012] External Links: Ensembl ID: ENSG00000128731 HGNC ID: HGNC:4868 Entrez Gene: 8924

Expression Profile of HERC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: