ctcRbase

Entry Detail

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General Information

Database ID: SKCM03855 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ZFX Full Name: zinc finger protein X-linked Category: mRNA Synonyms: ZNF926 Chromosome: chrX Strand: + Coordinate: Start Site(bp): 24149173 End Site(bp): 24216255 Gene Summary: This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010] External Links: Ensembl ID: ENSG00000005889 HGNC ID: HGNC:12869 Entrez Gene: 7543

Expression Profile of ZFX Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-139-5p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-223-3p YES NO YES hsa-miR-224-5p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-324-5p YES YES YES hsa-miR-329-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES NO YES hsa-miR-377-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-505-3p YES YES NO hsa-miR-543 YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-7-5p YES YES NO Display: