ctcRbase

Entry Detail

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General Information

Database ID: SKCM03930 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ELAVL1 Full Name: ELAV like RNA binding protein 1 Category: mRNA Synonyms: ELAV1|HUR|Hua|MelG Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 7958579 End Site(bp): 8005659 Gene Summary: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012] External Links: Ensembl ID: ENSG00000066044 HGNC ID: HGNC:3312 Entrez Gene: 1994

Expression Profile of ELAVL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-324-5p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-876-5p YES YES NO hsa-miR-9-5p YES YES YES Display: