ctcRbase

Entry Detail

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General Information

Database ID: SKCM03953 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GM2A Full Name: GM2 ganglioside activator Category: mRNA Synonyms: GM2-AP|SAP-3 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 151212150 End Site(bp): 151270440 Gene Summary: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] External Links: Ensembl ID: ENSG00000196743 HGNC ID: HGNC:4367 Entrez Gene: 2760

Expression Profile of GM2A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-382-5p YES YES YES Display: