Entry Detail



General Information

Database ID:SKCM03954
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:NKAP
Full Name:NFKB activating protein
Category:mRNA
Synonyms:-
Chromosome:chrX
Strand:-
Coordinate:
Start Site(bp):119920672End Site(bp):119943772
Gene Summary:This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]
External Links:
Ensembl ID:ENSG00000101882
HGNC ID:HGNC:29873
Entrez Gene:79576



Expression Profile of NKAP Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
YES
hsa-miR-129-5p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
NO
hsa-miR-320a
YES
YES
YES
hsa-miR-320b
YES
YES
YES
hsa-miR-320c
YES
YES
YES
hsa-miR-320d
YES
YES
YES
hsa-miR-424-5p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
hsa-miR-503-5p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
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