ctcRbase

Entry Detail

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General Information

Database ID: SKCM03963 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EZH2 Full Name: enhancer of zeste 2 polycomb repressive complex 2 subunit Category: mRNA Synonyms: ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 148807383 End Site(bp): 148884321 Gene Summary: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011] External Links: Ensembl ID: ENSG00000106462 HGNC ID: HGNC:3527 Entrez Gene: 2146

Expression Profile of EZH2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-124-3p YES NO YES hsa-miR-1297 YES YES YES hsa-miR-137 YES YES YES hsa-miR-138-5p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-217 YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-506-3p YES NO YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: