ctcRbase

Entry Detail

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General Information

Database ID: SKCM03966 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: STK10 Full Name: serine/threonine kinase 10 Category: mRNA Synonyms: LOK|PRO2729 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 172042073 End Site(bp): 172188386 Gene Summary: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000072786 HGNC ID: HGNC:11388 Entrez Gene: 6793

Expression Profile of STK10 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-429 YES YES NO Display: