ctcRbase

Entry Detail

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General Information

Database ID: SKCM03990 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BAG2 Full Name: BCL2 associated athanogene 2 Category: mRNA Synonyms: BAG-2|dJ417I1.2 Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 57172326 End Site(bp): 57189833 Gene Summary: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000112208 HGNC ID: HGNC:938 Entrez Gene: 9532

Expression Profile of BAG2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-137 YES YES NO hsa-miR-140-5p YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-506-3p YES YES NO Display: