ctcRbase

Entry Detail

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General Information

Database ID: SKCM04008 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SMC3 Full Name: structural maintenance of chromosomes 3 Category: mRNA Synonyms: BAM|BMH|CDLS3|CSPG6|HCAP|SMC3L1 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 110567691 End Site(bp): 110604636 Gene Summary: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000108055 HGNC ID: HGNC:2468 Entrez Gene: 9126

Expression Profile of SMC3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-150-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-708-5p YES YES NO hsa-miR-873-5p YES YES NO Display: