ctcRbase

Entry Detail

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General Information

Database ID: SKCM04018 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CDC73 Full Name: cell division cycle 73 Category: mRNA Synonyms: C1orf28|FIHP|HPTJT|HRPT1|HRPT2|HYX Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 193122017 End Site(bp): 193253901 Gene Summary: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009] External Links: Ensembl ID: ENSG00000134371 HGNC ID: HGNC:16783 Entrez Gene: 79577

Expression Profile of CDC73 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 NO YES YES hsa-miR-144-3p NO YES YES hsa-miR-149-5p YES YES YES hsa-miR-150-5p YES YES YES hsa-miR-155-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-188-5p YES NO YES hsa-miR-196a-5p NO YES YES hsa-miR-196b-5p NO YES YES hsa-miR-200b-3p NO YES YES hsa-miR-200c-3p NO YES YES hsa-miR-204-5p YES NO YES hsa-miR-211-5p YES NO YES hsa-miR-216b-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-26a-5p NO YES YES hsa-miR-26b-5p NO YES YES hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-329-3p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-340-5p YES NO YES hsa-miR-362-3p YES NO YES hsa-miR-371a-5p NO YES YES hsa-miR-374a-5p NO YES YES hsa-miR-374b-5p NO YES YES hsa-miR-381-3p YES YES NO hsa-miR-429 NO YES YES hsa-miR-489-3p YES NO YES hsa-miR-490-3p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-495-3p NO YES YES hsa-miR-655-3p YES NO YES hsa-miR-708-5p YES YES NO hsa-miR-9-5p YES YES YES Display: