ctcRbase

Entry Detail

---



General Information

Database ID: SKCM04093 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: VASP Full Name: vasodilator stimulated phosphoprotein Category: mRNA Synonyms: - Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 45506579 End Site(bp): 45526983 Gene Summary: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000125753 HGNC ID: HGNC:12652 Entrez Gene: 7408

Expression Profile of VASP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-124-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-150-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-211-5p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-376a-3p YES YES YES hsa-miR-376b-3p YES YES YES hsa-miR-491-5p YES NO YES hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-542-3p YES YES YES hsa-miR-613 YES YES YES hsa-miR-93-5p YES YES YES Display: