ctcRbase

Entry Detail

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General Information

Database ID: SKCM04117 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FADS1 Full Name: fatty acid desaturase 1 Category: mRNA Synonyms: D5D|FADS6|FADSD5|LLCDL1|TU12 Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 61799625 End Site(bp): 61829318 Gene Summary: The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000149485 HGNC ID: HGNC:3574 Entrez Gene: 3992

Expression Profile of FADS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1224-5p YES NO YES hsa-miR-122-5p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-128-3p YES NO YES hsa-miR-138-5p YES NO YES hsa-miR-140-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-495-3p YES NO YES hsa-miR-496 YES YES NO hsa-miR-96-5p YES YES NO Display: