ctcRbase

Entry Detail

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General Information

Database ID: SKCM04143 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NBPF14 Full Name: NBPF member 14 Category: mRNA Synonyms: DJ328E19.C1.1|NBPF Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 148531385 End Site(bp): 148679751 Gene Summary: This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, May 2013] External Links: Ensembl ID: ENSG00000270629 HGNC ID: HGNC:25232 Entrez Gene: 25832

Expression Profile of NBPF14 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-485-5p YES YES NO Display: