ctcRbase

Entry Detail

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General Information

Database ID: SKCM04184 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TXNDC5 Full Name: thioredoxin domain containing 5 Category: mRNA Synonyms: ENDOPDI|ERP46|HCC-2|HCC2|PDIA15|STRF8|UNQ364 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 7881517 End Site(bp): 7910814 Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. [provided by RefSeq, Dec 2016] External Links: Ensembl ID: ENSG00000239264 HGNC ID: HGNC:21073 Entrez Gene: 81567

Expression Profile of TXNDC5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-124-3p YES NO YES hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-183-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-300 YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-9-5p YES YES YES Display: