ctcRbase

Entry Detail

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General Information

Database ID: SKCM04200 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RHOG Full Name: ras homolog family member G Category: mRNA Synonyms: ARHG Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 3826978 End Site(bp): 3840983 Gene Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000177105 HGNC ID: HGNC:672 Entrez Gene: 391

Expression Profile of RHOG Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-331-3p YES NO YES hsa-miR-335-5p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-506-3p YES YES NO Display: