| ncRNA Symbol: | RP9 | | Full Name: | RP9, pre-mRNA splicing factor | | Category: | mRNA | | Synonyms: | PAP-1|PAP1 | | Chromosome: | chr7 | | Strand: | - | | Coordinate: | | Start Site(bp): | 33094797 | End Site(bp): | 33109401 |
| | Gene Summary: | The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. [provided by RefSeq, Sep 2009] | | External Links: | |
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