Entry Detail



General Information

Database ID:SKCM04213
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CHAC2
Full Name:ChaC cation transport regulator homolog 2
Category:mRNA
Synonyms:GCG1
Chromosome:chr2
Strand:+
Coordinate:
Start Site(bp):53767792End Site(bp):53775196
Gene Summary:The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis. [provided by RefSeq, Sep 2016]
External Links:
Ensembl ID:ENSG00000143942
HGNC ID:HGNC:32363
Entrez Gene:494143



Expression Profile of CHAC2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-101-3p
YES
YES
NO
hsa-miR-124-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-145-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-365a-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-599
YES
YES
NO
hsa-miR-98-5p
YES
YES
NO
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