ctcRbase

Entry Detail

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General Information

Database ID: SKCM04224 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: JMJD1C Full Name: jumonji domain containing 1C Category: mRNA Synonyms: KDM3C|TRIP-8|TRIP8 Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 63167221 End Site(bp): 63521850 Gene Summary: The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000171988 HGNC ID: HGNC:12313 Entrez Gene: 221037

Expression Profile of JMJD1C Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-138-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-182-5p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-802 YES NO YES hsa-miR-96-5p YES YES YES Display: